PhD position – University of Kent

Title: Investigating the co-evolution of chromosome organisation and gene expression in ruminants

Closing date: 18th January 2019

Project Description

Our lab aims to study genome evolution and the genetic changes associated with individual and species differences, applying the newest comparative and functional genomic techniques and the great wealth of genomic data available. In particular, we focus on the dynamics of chromosomal evolution in mammals and other vertebrates. To address these questions, we use rodents and ruminants as model species and take a multidisciplinary approach that combines experimental and bioinformatic analysis.

This project will focus particularly on how genomic changes between closely related ruminant species might affect gene expression. To do so, the student will first detect genomic changes in ruminants using an algorithm designed in our lab. Then, they will generate and analyse RNA-Seq data for cattle, sheep and red deer, to finally integrate their results with the gross genomic changes.

The candidate: We are seeking a highly motivated individual, excited by the prospect of conducting cutting-edge research, with a minimum of 2:1 degree in a relevant subject. She/he will have a strong willingness to work at the interface of wet-lab and bioinformatics, and demonstrate enthusiasm to learn new skills.

Informal enquiries can be sent at – m.farre-belmonte@kent.ac.uk

How to apply: Applications can be made using the online University application page where the project title should be entered as the proposed area of research and Dr Marta Farré Belmonte as supervisor. Please include a CV and a cover letter. https://www.kent.ac.uk/courses/postgraduate/how-to-apply/#research

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