postdoc in NZ with Neil Gemmell – molecular basis of sex reversal in sequentially hermaphroditic fish

Hi all,
great looking postdoc in Neil Gemmell’s lab at University of Otago, New Zealand.

Postdoctoral Opportunity – The molecular basis of sex reversal in sequentially hermaphroditic fish

We are currently seeking an outstanding postdoctoral researcher with interests in genetics, evolution, physiology and behavioural ecology to conduct research into the genetic basis of sex reversal in sequentially hermaphroditic fish.
Project Description: Most plants and animals irreversibly differentiate becoming either males or females. However, in some groups, notably fishes, individuals begin life as one sex and reverse sex sometime later in response to social cues (sequential hermaphrodism). Sex reversal in sequential hermaphrodites is complete, entailing radical restructuring of the gonad, alterations in morphology, and modifications to behaviour. The molecular basis of this stunning transformation is unknown, but is of intense interest, not only as a means to enhance our understanding of sex determination and differentiation, cellular commitment and tissue re-engineering, but also as a spectacular example of phenotypic plasticity in response to environment. Using the ubiquitous NZ spotty, together with two distant tropical relatives, the bluehead and three-spotted wrasse, both leading models for sex reversal, we will undertake a series of experiments to determine the genetic pathway underlying this stunning transformation. We will couple in the field ecological manipulations to produce a time series of samples taken during the process of sex reversal, with state-of-the art gene expression analyses and comparative genomic approaches, to identify both the primary trigger and subsequent genetic cascade that results in female-male sex reversal in fishes.
The project emerges from a new Marsden Grant headed by Professor Neil Gemmell and will be based in the Gemmell laboratory at the University of Otago.
The Ideal Candidate: Applications are invited from postdoctoral candidates who have experience in molecular biology, evolutionary and population genetics/genomics, and bioinformatics. The successful candidate will likely be
skilled in molecular genetic techniques and in the analysis of genetic data and associated statistics. They will be highly self-motivated and be able to work alongside a wide variety of people. In addition they will have a strong commitment to research excellence with a track record of high research productivity based on international, peer-reviewed publications commensurate for their career stage.
How to Apply: Interested applicants are encouraged to make informal enquiries to Professor Neil Gemmell. Please send your Curriculum Vitae, a sample of your written scientific work and the names of three referees with a covering
letter to: Professor Neil J. Gemmell
Formal Applications must be made at:
Salary Level and Range: Postdoctoral Fellow ($72,046)
Reference Number: 1400626
Closing Date: Thursday, 17 April 2014

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